Table 2 |
|
|
Binding Profiles of Opioid ligands in HEK-μ cells |
|
|
LIGAND |
AFFINITY Ki (nM) |
|
|
|
|
Cyclazocine |
0.22 ± 0.02 |
|
DAMGO |
2.65 ± 0.75 |
|
Morphine |
2.2 ± 0.5 |
|
Naltrexone |
0.74 ± 0.06 |
|
SKF 10047 |
1.15 ± 0.05 |
|
WIN 44,441 |
0.99 ± 0.31 |
|
Xorphanol |
0.25 ± 0.01 |
|
|
|
|
Competition binding assays were carried out in cell homogenates of HEK-μ cells as described under "Materials and Methods". Data represent mean ± SEM of Ki values from two or more independent experiments carried out in triplicate. |
|
|
Gharagozlou et al. BMC Pharmacology 2003 3:1 doi:10.1186/1471-2210-3-1 |
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