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Effect of Peperomia pellucida aqueous extract (EA) p.o. on rat paw edema induced by carragenaan on different plant phases, during winter. |
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| Treatment |
Rat paw volumes after 1, 2, 3, and 4 h after Carrageenan injection (mL) mean ± SEM (individual % inhibition) |
Edema % inhibition |
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| 1 h |
2 h |
3 h |
4 h |
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| Control |
0.463 ± 0.037 |
0.731 ± 0.085 |
0.819 ± 0.062 |
0.642 ± 0.049 |
- |
| Indomethacin 10 |
0.080 ± 0.011** (82.7) |
0.144 ± 0.018** (80.3) |
0.232 ± 0.052** (71.7) |
0.150 ± 0.059** (76.6) |
77.2 |
| Phenophase 1 |
0.232 ± 0.063* (49.9) |
0.355 ± 0.035* (51.4) |
0.552 ± 0.038* (32.6) |
0.399 ± 0.036* (37.9) |
42.0 |
| Phenophase 2 |
0.241 ± 0.039* (47.9) |
0.469 ± 0.040* (35.8) |
0.547 ± 0.024* (33.2) |
0.442 ± 0.031* (31.2) |
36.7 |
| Phenophase 3 |
0.412 ± 0.035 (11.0) |
0.532 ± 0.050 (27.2) |
0.621 ± 0.066 (24.2) |
0.527 ± 0.047 (17.9) |
21.1 |
| Phenophase 4 |
0.257 ± 0.064 (44.5) |
0.414 ± 0.074* (43.5) |
0.355 ± 0.061* (56.7) |
0.469 ± 0.066 (26.9) |
36.9 |
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Statistical significance: *p < 0.05, **p < 0.01 Vs control | |||||
Arrigoni-Blank et al. BMC Pharmacology 2002 2:12 doi:10.1186/1471-2210-2-12 |
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