Table 2

Effect of Peperomia pellucida aqueous extract (EA) p.o. on rat paw edema induced by carragenaan on different plant phases, during fall.

Treatment
Rat paw volumes after 1, 2, 3, and 4 h after Carrageenan injection (mL) mean ± SEM (individual % inhibition)
Edema % inhibition


1 h
2 h
3 h
4 h


Control
0.463 ± 0.037
0.731 ± 0.085
0.819 ± 0.062
0.642 ± 0.049
-
Indomethacin 10
0.080 ± 0.011** (82.7)
0.144 ± 0.018** (80.3)
0.232 ± 0.052** (71.7)
0.150 ± 0.059** (76.6)
77.2
Phenophase 1
0.431 ± 0.086 (6.9)
0.621 ± 0.061 (15.0)
0.794 ± 0.067 (3.1)
0.530 ± 0.063 (17.4)
10.5
Phenophase 2
0.351 ± 0.037 (24.2)
0.457 ± 0.024 (37.5)
0.502 ± 0.017** (38.7)
0.369 ± 0.021* (42.5)
36.7
Phenophase 3
0.306 ± 0.051* (33.9)
0.544 ± 0.064 (25.6)
0.639 ± 0.042* (22.0)
0.495 ± 0.043 (22.9)
25.3
Phenophase 4
0.226 ± 0.044** (51.2)
0.457 ± 0.038* (37.5)
0.545 ± 0.044** (33.5)
0.492 ± 0.039 (23.4)
34.4

Statistical significance: *p < 0.05, **p < 0.01 Vs control

Arrigoni-Blank et al. BMC Pharmacology 2002 2:12   doi:10.1186/1471-2210-2-12