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Resolution: standard / high Figure 5.
Concentration dependent effects of rasagiline, aminoindan and selegiline in the presence
of single stimuli (SS) or theta burst stimuli (TBS) after stimulation of the AMPA
glutamate receptor by fluorowillardiine (n = 4 slices +- SEM). Statistically significant attenuation of pop-spike amplitude in comparison to fluorowillardiine-induced
increases were obtained in the presence of 1 μM of rasagiline or aminoindan following
single stimuli (SS). During theta burst stimulation (TBS) already a concentration
of 1 μM of rasagiline or aminoindan became statistically significant. Stars indicate
statistical significance of p < 0.05 in comparison to control.
Dimpfel and Hoffmann BMC Pharmacology 2011 11:2 doi:10.1186/1471-2210-11-2 |