Borinate esters have dual effects on SOCE of myeloid and lymphoid hematopoietic cells. Dose response curves for 2-APB (A), DPBA (B) and 2-ABB (C) obtained on SOCE of BL-41, U937 and Jurkat cells. Same protocol was used as in figure 2A to generate the dose-response curve of [Ca2+]i increase after Ca2+ re-adding to borinate compound concentrations. Values are expressed as % of the peak [Ca2+]i increase measured in absence of any effector.
Dellis et al. BMC Pharmacology 2011 11:1 doi:10.1186/1471-2210-11-1