Hypothesis

Targeting ligand-gated ion channels in neurology and psychiatry: is pharmacological promiscuity an obstacle or an opportunity?

Matt T Bianchi¹^* and Emmanuel J Botzolakis²

¹ Neurology Department, Sleep Division, Massachusetts General Hospital, Boston, MA, USA

² Medical Scientist Training Program, Vanderbilt University School of Medicine, Nashville, TN, USA

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BMC Pharmacology 2010, 10:3 doi:10.1186/1471-2210-10-3

Published: 2 March 2010

Additional file 1:

Tables of modulator-target interactions. EC₅₀, IC₅₀, percent modulation, and references for each modulator-target interaction.

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