Table 2

Effect of natansnin on levels of serum enzymes induced by CCl4

ALT (IU/L)

ALP(IU/L)


Control

100

100


CCl4

238.26 ± 22.2a

244.82 ± 18.6a


Natansnin (20 mg/kg body wt)

108.26 ± 11.7

114.13 ± 10.9


Natansnin 10 mg + CCl4

173.45 ± 16.2a, b

162.27 ± 14.5a, b


Natansnin 20 mg + CCl4

165.61 ± 15.3a, b, c

145.61 ± 13.6a, b, c


Effect of CCl4 with or without prior administration of natansnin on levels of serum enzymes in liver. Values are expressed as percent response compared to control rats. The control values of ALT and ALP were 53.43 ± 3.6, 285.28 ± 18.2 IU/L respectively. a = Statistical significant at P < 0.05 as compare to control, b = Statistical significant at P < 0.05 as compare to CCl4, c = Statistical significant at P < 0.05 as compare to natansnin (10 mg) + CCl4.

Srilaxmi et al. BMC Pharmacology 2010 10:13   doi:10.1186/1471-2210-10-13

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