Effect of CCl4 with or without prior administration of natansnin on Catalase levels in liver homogenate and mitochondria. Catalase levels were estimated in homogenate and mitochondrial fractions from control, CCl4 and natansnin (10 mg/kg, 20 mg/kg body weight) treated rats. Values are given as percent control, and are mean ± S.D. of at least four animals. 0.3 mg of homogenate protein and 0.1 mg of mitochondrial protein were used for each assay. Catalase activity is expressed as nmols of H2O2 consumed per min per mg protein. The control values in homogenate and mitochondria are 733.9 ± 38.9, 1453 ± 64.6 respectively. a = Statistical significant at P < 0.05 as compare to control, b = Statistical significant at P < 0.05 as compare to CCl4, c = Statistical significant at P < 0.05 as compare to CCl4+ natansnin (10 mg).
Srilaxmi et al. BMC Pharmacology 2010 10:13 doi:10.1186/1471-2210-10-13