|
Inhibitory concentrations 50% (IC50) and maximal inhibition of cell growth of different breast and prostate cancer cell lines by receptorphin. |
||||
| Receptorphin |
Maximum Inhibition |
Receptorphin+ Diprenorphin |
Maximum Inhibition |
|
|
|
||||
| MCF7 |
1.51 ± 0.18 × 10-10 |
0.41 |
1.69 ± 0.10 × 10-9 |
0.49 |
| T47D |
7.01 ± 0.36 × 10-11 |
0.44 |
3.61 ± 0.13 × 10-9 |
0.48 |
| LNCaP |
8.70 ± 0.87 × 10-8 |
0.58 |
2.88 ± 0.15 × 10-9 |
0.61 |
| DU145 |
4.36 ± 0.19 × 10-10 |
0.59 |
3.44 ± 2.32 × 10-7 |
0.53 |
| PC3 |
6.98 ± 0.11 × 10-9 |
0.27 |
7.00 ± 0.14 × 10-7 |
0.31 |
|
Curves were obtained by sigmoidal fitting of data presented in Figure 2. Concentrations are expressed in Moles/L. Mean ± SE of three different experiments performed in triplicate. | ||||
Kampa et al. BMC Pharmacology 2001 1:9 doi:10.1186/1471-2210-1-9 |
||||