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Theoretical CNBr fragments of the α1-subunit of the sGC. MW: molecular weight; AA: amino acid; the several amino acids are shown in the one-letter-code. |
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| CNBr fragment |
MW [kDa] |
AA number |
AA position in the α1 subunit |
Sequence from the N-terminus |
|
|
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| CNBr-1 |
24 |
215 |
21–235 |
APGQVPTEPIEE... |
| CNBr -2 |
6.2 |
54 |
236–290 |
PPCFRSECTEFV... |
| CNBr -3 |
5.5 |
47 |
291–338 |
LDRDLAILQLG... |
| CNBr -4 |
0.2 |
2 |
339–340 |
TM |
| CNBr -5 |
0.3 |
3 |
341–343 |
LNM |
| CNBr -6 |
2.5 |
19 |
344–363 |
QFVIRVRRWDNL... |
| CNBr -7 |
0.6 |
6 |
364–369 |
DLKGQM |
| CNBr -8 |
12.5 |
111 |
370–481 |
IYIVESSAILFLG... |
| CNBr -9 |
2.4 |
22 |
482–504 |
LFSDIVGFTAICS... |
| CNBr -10 |
5.2 |
46 |
505–551 |
LNALYTRFDQQ... |
| CNBr -11 |
0.4 |
4 |
552–555 |
ALKM |
| CNBr -12 |
0.1 |
1 |
556 |
M |
| CNBr -13 |
0.8 |
7 |
557–563 |
ELSNEVM |
| CNBr -14 |
0.9 |
9 |
564–572 |
SPHGEPIKM |
| CNBr -15 |
1.8 |
17 |
573–590 |
RIGLHSGSVFAG... |
| CNBr -16 |
11.2 |
99 |
591–690 |
PRYCLFGNNVT... |
Becker et al. BMC Pharmacology 2001 1:13 doi:10.1186/1471-2210-1-13 |
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