Table 1 |
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|
Pharmacokinetics of artesunate and dihydroartemisinin in rats having received a single dose of artesunate |
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|
Drug |
Cmax (ng/ml) |
Tmax (min) |
AUC0-t (ngmin/ml) |
T1/2 absorption (min) |
|
|
||||
|
Artesunate |
713.1 ± 233.3 |
5.0 ± 0.0 |
18968 ± 8012.4 |
2.73 +/- 0.85 |
|
Dihydroartemisinin |
2040.3 ± 650.0 |
37.5 ± 8.7 |
74500 ± 16806.1 |
12.49 +/- 2.49 |
|
|
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|
Olliaro et al. BMC Pharmacology 2001 1:12 doi:10.1186/1471-2210-1-12 |
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