Table 1

Pharmacokinetics of artesunate and dihydroartemisinin in rats having received a single dose of artesunate

Drug
Cmax (ng/ml)
Tmax (min)
AUC0-t (ngmin/ml)
T1/2 absorption (min)

Artesunate
713.1 ± 233.3
5.0 ± 0.0
18968 ± 8012.4
2.73 +/- 0.85
Dihydroartemisinin
2040.3 ± 650.0
37.5 ± 8.7
74500 ± 16806.1
12.49 +/- 2.49

Olliaro et al. BMC Pharmacology 2001 1:12   doi:10.1186/1471-2210-1-12