Figure 1.

Model of NR2 Subunit. 1.A: Schematic of vertebrate NR2A or NR2B subunits. Note the long intracellular C-terminal domain and relative positioning of particular interacting proteins. PSD-95 is a scaffolding protein, while CaMKII and P13K are kinases that phosphorylate the NMDA receptor. 1.B: Schematic of invertebrate NR2. Note the significantly shorter intracellular C-terminus.