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Environmental enrichment did not ameliorate the effects of the HD mutation on body and brain weight at 9 months of age. The HD transgene affected both body weight (P < 0.001) and brain weight (P < 0.001), relative to WT littermates. NE: non-enriched (standard housed); EE: environmentally enriched. |
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| WT |
HD |
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| EE |
NE |
EE |
NE |
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| Body weight (grams) |
36.74 ± 1.75 |
40.02 ± 2.24 |
20.73 ± 0.56 |
21.24 ± 0.98 |
| Brain weight (grams) |
0.44 ± 0.013 |
0.45 ± 0.008 |
0.34 ± 0.013 |
0.36 ± 0.012 |
van Dellen et al. BMC Neuroscience 2008 9:34 doi:10.1186/1471-2202-9-34 |
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