Table 3

Ontologic classification of genes differentially expressed at 28d.

Category

Number of sequences

% of total

p-value


Cadherin-like

13

3.40%

1.30E-14

cell-cell adhesion

18

4.70%

4.10E-07

Synapse formation

regulation of cell proliferation

20

5.20%

5.70E-04

neurogenesis

15

3.90%

7.60E-03

morphogenesis

34

8.90%

2.70E-03

neuron differentiation

15

3.90%

2.80E-03

Apoptosis

regulation of apoptosis

22

5.80%

1.80E-04

negative regulation of apoptosis

12

3.10%

8.90E-04

Regulatory pathways

calcium ion binding

31

8.10%

2.60E-06

ion binding

62

16.30%

5.50E-04

transmission of nerve impulse

20

5.20%

4.90E-04

actin polymerization and/or depolymerization

7

1.80%

2.40E-04

cytoskeleton organization and biogenesis

18

4.70%

1.70E-03

nerve ensheathment

5

1.30%

4.30E-03

Enzyme

phosphorylation

39

10.20%

9.50E-04

acetylation

14

3.70%

3.20E-03


Functional analysis of differentially expressed transcript employed DAVID tools (see Methods for detailed description). To calculate background, Affychip has been used. Some transcripts represent in more than one category. Cutoff value for category selection p < 0.05.

Yukhananov and Kissin BMC Neuroscience 2008 9:32   doi:10.1186/1471-2202-9-32

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