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Ontologic classification of genes differentially expressed at 28d. |
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| Category |
Number of sequences |
% of total |
p-value |
|
|
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| Cadherin-like |
13 |
3.40% |
1.30E-14 |
| cell-cell adhesion |
18 |
4.70% |
4.10E-07 |
| Synapse formation |
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| regulation of cell proliferation |
20 |
5.20% |
5.70E-04 |
| neurogenesis |
15 |
3.90% |
7.60E-03 |
| morphogenesis |
34 |
8.90% |
2.70E-03 |
| neuron differentiation |
15 |
3.90% |
2.80E-03 |
| Apoptosis |
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| regulation of apoptosis |
22 |
5.80% |
1.80E-04 |
| negative regulation of apoptosis |
12 |
3.10% |
8.90E-04 |
| Regulatory pathways |
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| calcium ion binding |
31 |
8.10% |
2.60E-06 |
| ion binding |
62 |
16.30% |
5.50E-04 |
| transmission of nerve impulse |
20 |
5.20% |
4.90E-04 |
| actin polymerization and/or depolymerization |
7 |
1.80% |
2.40E-04 |
| cytoskeleton organization and biogenesis |
18 |
4.70% |
1.70E-03 |
| nerve ensheathment |
5 |
1.30% |
4.30E-03 |
| Enzyme |
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| phosphorylation |
39 |
10.20% |
9.50E-04 |
| acetylation |
14 |
3.70% |
3.20E-03 |
|
Functional analysis of differentially expressed transcript employed DAVID tools (see Methods for detailed description). To calculate background, Affychip has been used. Some transcripts represent in more than one category. Cutoff value for category selection p < 0.05. | |||
Yukhananov and Kissin BMC Neuroscience 2008 9:32 doi:10.1186/1471-2202-9-32 |
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