Additional file 1.

Control immunohistochemistry without primary antibody for 6E10 staining. Low power (2×) micrograph demonstrates the lack of non-specific staining in neocortex and hippocampus with biotynalated goat anti-mouse secondary antibody (Vector Laboratories: Burlingame, CA) following no primary negative control for immunohistochemistry with human-specific APP mouse monoclonal antibody 6E10 (Signet; Dedham, MA).

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Agca et al. BMC Neuroscience 2008 9:28   doi:10.1186/1471-2202-9-28