  Research articleDevelopment of transgenic rats producing human β-amyloid precursor protein as a model for Alzheimer's disease: Transgene and endogenous APP genes are regulated tissue-specificallyCansu Agca1 1University of Missouri College of Veterinary Medicine, Department of Veterinary Pathobiology Columbia, MO 65211, USA 2Department of Neurology and Center for Neurodegenerative Disease, Emory University, Atlanta, GA 30322, USA 3Yerkes National Primate Research Center, Emory University, Atlanta, GA 30329, USA
BMC Neuroscience 2008, 9:28doi:10.1186/1471-2202-9-28
Additional filesAdditional file 1: Control immunohistochemistry without primary antibody for 6E10 staining. Low power (2×) micrograph demonstrates the lack of non-specific staining in neocortex and hippocampus with biotynalated goat anti-mouse secondary antibody (Vector Laboratories: Burlingame, CA) following no primary negative control for immunohistochemistry with human-specific APP mouse monoclonal antibody 6E10 (Signet; Dedham, MA). Format: DOC Size: 2.1MB Download file This file can be viewed with: Microsoft Word Viewer |
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