Quantification of neuronal TDP-43 nuclear speckles in spinal cord sections. Approximately 0.9 μm thick confocal section through representative motor neuron nucleus (a) and automatic setting of brightness and contrast in Image J (b). No significant difference in TDP-43 speckle number is obvious between genotypes (c).
Turner et al. BMC Neuroscience 2008 9:104 doi:10.1186/1471-2202-9-104