ReNcell VM current-voltage responses following preD. A, B) Example of firing elicited by stepping the current command in 20 pA steps (400 ms duration) from a resting potential of ~-75 mV in ReNcell VM 10 days after differentiation was started in control solution (A) and after adding 0.6 μM TTX (B). C, D) Same cell as in (A, B) responding with inward currents to incremental voltage steps (10 mV, from -60 mV to + 30 mV, 400 ms duration), before (C) and after (D) adding 0.6 μM TTX to the control solution. E) Average inward current-voltage relationships in control differentiated (solid squares) and after adding 0.6 μM TTX (open squares) and F) average steady-state current-voltage relationship for control (solid squares) and TTX treated (open squares).
Donato et al. BMC Neuroscience 2007 8:36 doi:10.1186/1471-2202-8-36