Figure 5.

A drawing exemplifying the active "stand-by" status of cells exposed to the various stressful events involved in AD apoptosis. Neuronal death occurs when the cell(s) reaches a point of "No-return", where an overwhelming mitochondria pressure is no longer compensated by the many protective pathways that the cell(s) has adopted.

Alberghina and Colangelo BMC Neuroscience 2006 7(Suppl 1):S2   doi:10.1186/1471-2202-7-S1-S2