Figure 8.

Syntaxin 2 is primarily localized outside presynaptic terminals. A–C: Syntaxin 2 is rarely localized to conventional presynaptic terminals in the inner plexiform layer (IPL). Syntaxin 2-positive puncta (arrows) do not colocalize with conventional synapses labeled for synapsin 1 (arrowheads). However, syntaxin 2-positive puncta are often closely apposed to synapsin I-positive presynaptic terminals (circles). Images shown from a projection of 9 optical sections with total thickness of 1.16 μm. D–F: Syntaxin 2 labeling (arrows) does not colocalize with labeling for the presynaptic active zone protein, bassoon (arrowheads). However, syntaxin 2-positive puncta are frequently apposed to bassoon-positive synaptic active zones. Images shown is a projection of 14 optical sections with total thickness of 1.89 μm. G–I: Syntaxin 2 is not expressed in bipolar cell terminals. Syntaxin 2 labeling (arrows) does not colocalize with labeling for VGLUT1 (arrowheads) in bipolar cell terminals. However, syntaxin 2-positive puncta are frequently closely apposed to VGLUT1-positive bipolar cell terminals. Images shown from a projection of 11 optical sections with total thickness of 1.45 μm. INL, inner nuclear layer, GCL, ganglion cell layer. Scale bars = 5 μm for A–C; 10 μm for D–I.

Sherry et al. BMC Neuroscience 2006 7:54   doi:10.1186/1471-2202-7-54
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