Figure 1.

Ketone levels, body weight motor function. (A) The serum content of total ketone bodies (DHB and acetoacetate) in SOD1-G93A transgenic mice. (data = mean ± se; standard diet: n = 5, KD: n = 6; * - p < 0.05). (B) The serum content of DHB in SOD1-G93A transgenic mice. (data = mean ± se; standard diet: n = 5, KD: n = 6; * - p < 0.05). (C) Time to failure (50% baseline performance) in SOD1-G93A transgenic mice fed a KD compared to standard diet from 85 days to 136 days of age. (data = mean ± se; standard diet: n = 5, KD: n = 6; p = 0.027). (D) The effect of the KD on weight in SOD1-G93A mice at the beginning of treatment (Day 50), presymptomatic (Day 89) and endpoint of the study. (data = mean ± se; standard diet: n = 5, KD: n = 6[AV3]; p = 0.047).

Zhao et al. BMC Neuroscience 2006 7:29   doi:10.1186/1471-2202-7-29
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