Astrocyte Expression of SDF-1. GFAP and SDF-1 dual labeling is demonstrated by confocal microscopy in P10 mice, three days post-HI. Panels A-C, from the striatum, show perivascular (arrowheads) astrocyte (GFAP – green) expression of SDF-1 (red). Panels D-F, from the hippocampus, show (arrowhead) similar co-labeling of GFAP (green) astrocyte cell bodies and processes for SDF-1 (red). Panels C and F show GFAP and SDF-1 co-labeling in merged orthogonal views of confocal z stacks. GFAP staining is shown in green and SDF-1 staining in Red. Panels A, B, D, and E are single z plane field images captured with a 63× objective. Scale bar equals 50 μm.
Miller et al. BMC Neuroscience 2005 6:63 doi:10.1186/1471-2202-6-63