Table 3

Cholinergic agonists and antagonists used in this study

Agonist

Site of Action

Induced Pigment Granule Dispersion

Carbachol

M1-M5

Yes

4-Chlorophenyl

M1

Yes

Arecaidine but-2-ynyl ester tosylate

M2

No

Antagonist

Site of Action

Blocked Pigment Granule Dispersion

Atropine

M1-M5

Yes

Pirenzepine

M1

Yes

AF-DX 116

M2

No

4-DAMP

M3

Yes

Tropicamide

M4

No

RPE was isolated from dark-adapted bluegill and, following incubation for 45 minutes in 10 μM forskolin, was incubated an additional 45 minutes in increasing concentrations of agonist or in the presence of 100 nM carbachol and increasing concentrations of antagonists. The agonists and antagonists tested and their efficacy are presented.

González et al. BMC Neuroscience 2004 5:23   doi:10.1186/1471-2202-5-23