Figure 4.

S3 and S4 co-localize with ezrin in nodal regions of PNS. (A) Sections through rat sciatic nerve at p30 were labeled with antibodies to ezrin (Ez, red) and to paranodin/Caspr (Pnd, green), a marker of paranodal regions. (B, C) Sections were double labeled with antibodies to S3 (B, green) or S4 (C, green) and antibodies to ezrin (Ez, red). Superposition of syndecan and ezrin labelings is shown (merge). Two different nodes are shown in each case. B, C: confocal stacks. Scale bars: 4 μm (A), 1 μm (B, C).