|
Quantities of PS, SWS and W after NaCl and MCH ICV injections. |
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| Hours post-injection |
0–2 |
2–4 |
4–6 |
6–8 |
|
|
|
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| PS |
NaCl |
3.4 ± 0.8 |
5.6 ± 1 |
10.8 ± 2.1 |
10.7 ± 2.1 |
| 0.02 μg |
8 ± 2 * |
11 ± 0.6 * |
13.1 ± 2.1 |
9.4 ± 4.3 |
|
| 0.2 μg |
10.1 ± 2.3 ** |
12.2 ± 2.6 * |
15.6 ± 2.6 |
19.4 ± 3.3 * |
|
| 1 μg |
9.3 ± 2.2 ** |
12.5 ± 3.2 * |
13.3 ± 2.4 |
11.3 ± 2.6 |
|
| 5 μg |
5 ± 0.8 |
12.2 ± 2.3 ** |
12.4 ± 3.1 |
11.5 ± 2.4 |
|
| 10 μg |
5.8 ± 2.3 |
9.5 ± 1.5 |
10.8 ± 3.1 |
10.7 ± 3.2 |
|
| SWS |
NaCl |
23.5 ± 4.4 |
39.1 ± 4.8 |
43 ± 5.2 |
44.7 ± 5.6 |
| 0.02 μg |
34.9 ± 5.8 |
34.6 ± 2.5 |
49.1 ± 2.1 |
39.3 ± 5.2 |
|
| 0.2 μg |
39.8 ± 3.8 * |
45.1 ± 7.3 |
51 ± 7.1 |
55.6 ± 7 |
|
| 1 μg |
40.7 ± 7.1 * |
59.2 ± 8.4 * |
61.7 ± 4.6 * |
56.6 ± 5.9 |
|
| 5 μg |
26.8 ± 5 |
45.9 ± 6.4 |
46.7 ± 7.2 |
40.8 ± 4.1 |
|
| 10 μg |
37.2 ± 7.8 |
55.4 ± 11.7 |
57.3 ± 3.4 |
51.1 ± 4.7 |
|
| W |
NaCl |
93.5 ± 4.7 |
74 ± 5.4 |
66.9 ± 6.8 |
64.7 ± 7.3 |
| 0.02 μg |
77.1 ± 7.8 |
74.5 ± 2.4 |
57.8 ± 2.3 |
71.3 ± 9.5 |
|
| 0.2 μg |
70.1 ± 6 ** |
62.6 ± 7.6 |
53.3 ± 9.3 |
45 ± 9.7 |
|
| 1 μg |
70.1 ± 8.6 * |
48.3 ± 9 * |
45 ± 5.2 * |
52.1 ± 7.8 |
|
| 5 μg |
91.4 ± 6.7 |
63.1 ± 7.4 |
59.7 ± 10.1 |
68.3 ± 5.7 |
|
| 10 μg |
74.8 ± 10.6 |
55.2 ± 10.8 |
49.4 ± 2.4 |
56.5 ± 6.8 |
|
|
The quantities (mean ± SEM) of PS, SWS, and W following NaCl or MCH administrations are reported in minutes per 2 hours. Significance values indicated for individual points compared to NaCl are * p < 0.05 and ** p < 0.01. | |||||
Verret et al. BMC Neuroscience 2003 4:19 doi:10.1186/1471-2202-4-19 |
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