Table 2 |
|
|
Binding Profile of Opioid ligands in HEK-δ cells |
|
|
LIGAND |
AFFINITY Ki (nM) |
|
|
|
|
DPDPE |
0.7 ± 0.3 |
|
Fentanyl |
242.5 ± 102.5 |
|
Morphine |
68.5 ± 19.5 |
|
Nalbuphine |
77 ± 8 |
|
Nalorphine |
38.5 ± 4.0 |
|
WIN 44,441 |
2.6 ± 0.9 |
|
Xorphanol |
1.0 ± 0.2 |
|
|
|
|
Competition binding assays were carried out in cell homogenates of HEK-δ cells as described under Methods. Data represent mean ± SEM. of Ki values from two or more independent experiments carried out in triplicate. |
|
|
Gharagozlou et al. BMC Neuroscience 2002 3:19 doi:10.1186/1471-2202-3-19 |
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