Figure 4.

Decreasing AGRP levels by pSUPER-AGRPi construct decreases body weight (a) Mice transfected with the pSUPER-AGRPi construct shows persistent loss of body weight after transfection while the mice transfected with the control vector recover body weight over a course of six days (n = 14; p < 0.0001). (b) pSUPER-RNAI targeted to AGRP has no effect on mean daily food intake (n = 14; p = 1.6992).

Makimura et al. BMC Neuroscience 2002 3:18   doi:10.1186/1471-2202-3-18
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