Inflammation in the brain of mice with EAE: effect of previous infection with S. aureus. C57BL/6 mice were infected with S. aureus TSST-1+ and TOX-, and 3 days later, they were subjected to EAE induction. Brain inflammatory infiltrates in mice with EAE (a, b), mice previously infected with S. aureus TSST-1 strain subjected to EAE (c, d) and mice previously infected with S. aureus TOX- strain subjected to EAE (e, f) were evaluated 30 days after disease induction. The panel is representative of 6-7 animals/group. Magnification is 10 x and 100 x in the left and right panel, respectively.
França et al. BMC Neuroscience 2014 15:8 doi:10.1186/1471-2202-15-8