Chronic alcohol consumption leads to a decrease of motor activity in mice. Upper panels (A and B): locomotion; lower panels (C and D): rearing. Time course of locomotion (A) and rearing (C) are shown as beam breaks per 5 min. Cumulative locomotion (B) and rearing (D) for the entire period (0–60 min) are shown. Data are expressed as mean ± S.E.M. (n = 19 for the alcohol group, n = 8 for the water-only control group). *, significant difference compared with the water-only control group (p < 0.05, unpaired t-test).
Zou et al. BMC Neuroscience 2014 15:61 doi:10.1186/1471-2202-15-61