Table 2

Average morphometric data of the renal nerves fascicles from the six experimental groups: acute diabetic group (15 days after STZ injection), acute treated group, acute control group, chronic diabetic group (12 weeks after STZ injection), chronic treated group and chronic control group
Acute diabetic Acute treated Acute control Chronic diabetic Chronic treated Chronic control
Fascicular area (μm2) 5030 ± 1200 4470 ± 619 3585 ± 672 7834 ± 1103* 6212 ± 547 5300 ± 1177
Fascicular diameter (μm) 76 ± 9 74 ± 5 64 ± 7 124 ± 19* 88 ± 4 83 ± 12
Myelinated fiber number 6 ± 2 9 ± 2 6 ± 1° 10 ± 3 13 ± 2 19 ± 7
Myelinated fiber density (number of fiber/μm2) 1470 ± 411 2113 ± 441 1949 ± 759 1333 ± 295° 2105 ± 292 3885 ± 1124
Schwann cell nucleus number 34 ± 4 24 ± 4 32 ± 6 44 ± 8 42 ± 3+ 38 ± 7
Schwann cell nucleus density (number of nucleus/μm2) 9043 ± 1420 6013 ± 950 10650 ± 1752 5517 ± 544* 6897 ± 662 8424 ± 1606
Unmyelinated fiber number 1821 ± 330 2289 ± 342 1322 ± 230 1481 ± 175 1573 ± 218 1237 ± 98
Unmyelinated fiber density (number of fiber/μm2) 408219 ± 41358+ 578601 ± 96603 379066 ± 38120+° 211857 ± 31431° 256855 ± 33371+° 288967 ± 31934

*Indicates difference compared to acute diabetic group, +indicates difference compared to acute treated, °indicates difference compared to chronic control.

Sato et al.

Sato et al. BMC Neuroscience 2014 15:5   doi:10.1186/1471-2202-15-5

Open Data