Unmyelinated fiber distribution on acute (A) and chronic (B) treated and untreated diabetic groups and respective controls. Average values are represented. The distributions are unimodal in all groups with the peak at 0.7 μm for acute groups and chronic control group. For the chronic diabetic groups, treated and untreated, there is a shift (One Way ANOVA on Ranks, p < 0.001) of the peak to 0.9 μm, indicating a loss of the small fibers.
Sato et al. BMC Neuroscience 2014 15:5 doi:10.1186/1471-2202-15-5