Open Access Highly Accessed Research article

A two years longitudinal study of a transgenic Huntington disease monkey

Anthony WS Chan12*, Yan Xu12, Jie Jiang12, Tayeb Rahim1, Dongming Zhao12, Jannet Kocerha12, Tim Chi1, Sean Moran1, Heidi Engelhardt1, Katherine Larkin1, Adam Neumann1, Haiying Cheng12, Chunxia Li3, Katie Nelson1, Heather Banta1, Stuart M Zola14, Francois Villinger56, Jinjing Yang12, Claudia M Testa7, Hui Mao8, Xiaodong Zhang13 and Jocelyne Bachevalier109*

Author Affiliations

1 Division of Neuropharmacology and Neurologic Diseases, Yerkes National Primate Research Center, Emory University, Atlanta, Georgia

2 Department of Human Genetics, Emory University School of Medicine, Atlanta, Georgia

3 Yerkes Imaging Center, Yerkes National Primate Research Center, Emory University, Atlanta, Georgia

4 Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, Georgia

5 Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia

6 Division of Pathology, Yerkes National Primate Center, Emory University, Atlanta, Georgia

7 Department of Neurology, Emory University School of Medicine, Atlanta, Georgia

8 Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, Georgia

9 Department of Psychology, Emory University School of Medicine, Atlanta, Georgia

10 Division of Developmental and Cognitive Neuroscience, Yerkes National Primate Center, Emory University, Atlanta, Georgia

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BMC Neuroscience 2014, 15:36  doi:10.1186/1471-2202-15-36

Published: 3 March 2014

Additional files

Additional file 1: Table S1:

Huntington’s Disease Primate Motor Rating Score (HDPMRS). Table S2. Behavioral testing schedule. Table S3. INAS behaviors and rating scale. Table S4. Definitions of behavioral measures in the Detour-Reaching Task.

Format: DOCX Size: 33KB Download file

Open Data

Additional file 2:

Supplemental Methods: Behavioral Testing.

Format: DOCX Size: 40KB Download file

Open Data