Table 3

Summary of the variations from PFC metabolites in mice
Metabolites Chemical shift Control-nicotine
(ppm) VIPa Loadingb
Cystine 3.36 5.83 -0.354
Arginine 3.76 2.90 +0.217
Glucose 3.40 2.52 -0.074
Glutamate 2.04 2.06 +0.156
3-Hydroxybutyric acid 1.20 2.05 -0.151
Uracil 7.52 2.03 -0.151
NAD 8.84 1.99 -0.150
Acetone 2.24 1.92 +0.145
Phosphocholine 4.16 1.83 +0.135
L-Phenvlalanine 3.12 1.80 -0.133

aVariable importance in the projection (VIP ≥ 1) was obtained from OSC-PLS.

bLoading: the positive (+) value represents an increase of the metabolite in the second group of the subtitle (e.g.: Control → Nicotine), while the negative (-) value represents a decrease of the metabolite in the second group of the subtitle.

Li et al.

Li et al. BMC Neuroscience 2014 15:32   doi:10.1186/1471-2202-15-32

Open Data