Table 1

Summary of the significant pERK1, pERK2, P-p90RSK and c-Fos findings in mouse prefrontal cortex and striatum following aripiprazole and quetiapine treatment over 24 hours
APD Brain region Protein 20 min 60 min 240 min 480 min 24/24
Aripiprazole Prefrontal cortex pERK1 - -
pERK2 - - -
P-p90RSK - - - - -
c-Fos - - - -
Striatum pERK1 - - - - -
pERK2 - - - - -
P-p90RSK - - - - -
c-Fos - - -
Quetiapine Prefrontal cortex pERK1 - - - - -
pERK2 - - - - -
P-p90RSK - - - -
c-Fos - - - -
Striatum pERK1 - - - -
pERK2 - - - - -
P-p90RSK - - -
c-Fos - - - -

↓ = significantly decreased protein phosphorylation.

↑ = significantly increased protein phosphorylation.

- = no significant change.

APD = antipsychotic drug, min = minutes.

Pereira et al.

Pereira et al. BMC Neuroscience 2014 15:30   doi:10.1186/1471-2202-15-30

Open Data