The effect of picroside II on the transcription of MBP mRNA detected by RT-PCR. GAPDH was used as a loading parameter. “m” presented marker. Line 1–16 were the treatment group rats which were treated in different time with different doses. In model group (M), the RAM of MBP mRNA was significantly decreased than that in control group (C) (##P < 0.05), while it was markedly increased after treatment (**P < 0.05 vs model group).
Zhao et al. BMC Neuroscience 2014 15:25 doi:10.1186/1471-2202-15-25