Myelin nerve fibers in parietal white matter of rats, FGS × 400. Normal myelin (A) showed cord-like, dark green, tightly packed, and cells was red (Red arrow); it showed myelin fibers loose and light-stained, glial cell vacuolation (Black arrow) after modeling (B). In model group, myelin gray value (MGV) decreased significantly than that in control group (#P < 0.05 vs control group) and increased significantly than that in model group after treatment (C) (*P < 0.05 vs model group). The expression of MBP in parietal white matter, SABC × 400. In the control group (D), myelin fibers was arranged closely and tidy. After modeling (E), myelin degeneration release and disordered, positive cells showed cytoplasmic uneven coloring, and vesicular (Black arrow). The MBP expressed significantly lower in model group (##P < 0.05 vs control group) and increased significantly and myelin fibers tightly packed in treatment group (F) (**P < 0.05 vs model group).
Zhao et al. BMC Neuroscience 2014 15:25 doi:10.1186/1471-2202-15-25