Representative micrographs showing astrocytes and microglia in HE rats. The left column was GFAP-immunoreactive astrocytes (A-C) and right column was Iba1-immunoreactive microglia (D-F) in sham control (A and D), BDL (B and E) and BDLHD (C and F). At a high magnification, thickened processes (*) and bouton-like terminals (arrow) were easily identified in BDL and BDLHD rats. The polyclonal Iba1 antibodies labeled both inactive microglia (insert of D) and activated microglia (inserts of E and F). Bar = 300 μm in A-C, 20 μm for inserts.
Chen et al. BMC Neuroscience 2014 15:15 doi:10.1186/1471-2202-15-15