Email updates

Keep up to date with the latest news and content from BMC Neuroscience and BioMed Central.

Open Access Highly Accessed Research article

SYNTAX score effect on electroencephalography power dynamics in patients undergoing on-pump coronary artery bypass grafting

Irina V Tarasova1*, Roman S Tarasov2, Olga A Trubnikova2, Olga L Barbarash3 and Leonid S Barbarash4

Author Affiliations

1 Department of Cardiovascular Diagnostics, Research Institute for Complex Issues of Cardiovascular Diseases, Russian Academy of Medical Sciences, Siberian Branch, Kemerovo, Russian Federation

2 Department of Multifocal Atherosclerosis, Research Institute for Complex Issues of Cardiovascular Diseases, Russian Academy of Medical Sciences, Siberian Branch, Kemerovo, Russian Federation

3 Director of Research Institute for Complex Issues of Cardiovascular Diseases, Russian Academy of Medical Sciences, Siberian Branch, Kemerovo, Russian Federation

4 Chief Scientist of Research Institute for Complex Issues of Cardiovascular Diseases, Russian Academy of Medical Sciences, Siberian Branch, Kemerovo, Russian Federation

For all author emails, please log on.

BMC Neuroscience 2013, 14:95  doi:10.1186/1471-2202-14-95

Published: 6 September 2013

Abstract

Background

The severity of angiographically assessed coronary artery disease may be the factor that influences the degree of brain damage during on-pump surgery. Modern technology such as computed electroencephalography (EEG) that is used to detect signs of brain damage could also be used to determine the advantages and disadvantages of various surgical myocardial revascularization methods in certain categories of patients. The present study investigated EEG power dynamics for 1 postoperative month in patients undergoing on-pump coronary artery bypass grafting (CABG) who were divided into two groups: those with moderate coronary lesions (SYNTAX score ≤ 22, n = 12) and those with severe coronary lesions (SYNTAX score ≥ 23, n = 18).

Results

At 7–10 days after CABG, all patients showed theta type 1 rhythm power higher than that seen preoperatively, possibly indicating that brain damage occurred during bypass. At 1 month after CABG, the theta type 1 rhythm power had decreased to the baseline level in patients with SYNTAX scores of ≤22, whereas it had increased in patients with SYNTAX scores ≥23.

Conclusions

SYNTAX scores ≥ 23 are associated with EEG markers of perioperative brain damage during CABG. Careful preoperative assessment, preparation, and more effective intraoperative brain protection are essential for this category of coronary heart disease (CHD) patients.

Keywords:
Electroencephalography; Brain damage; Theta rhythm power; SYNTAX score; On-pump coronary artery bypass grafting