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The duration of sleep promoting efficacy by dual orexin receptor antagonists is dependent upon receptor occupancy threshold

Anthony L Gotter, Christopher J Winrow, Joseph Brunner, Susan L Garson, Steven V Fox, Jacquelyn Binns, Charles M Harrell, Donghui Cui, Ka Lai Yee, Mark Stiteler, Joanne Stevens, Alan Savitz, Pamela L Tannenbaum, Spencer J Tye, Terrence McDonald, Leon Yao, Scott D Kuduk, Jason Uslaner, Paul J Coleman and John J Renger*

BMC Neuroscience 2013, 14:90  doi:10.1186/1471-2202-14-90

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