Microinjection of κ-opiate receptor agonist and DA depletion had no effect on nociceptive responses in PFC. A: (a) The top trace represents ECoG. The second trace is multiple unit discharges evoked by mechanical stimulation. The third trace represents single unit responses selected by cluster analysis from multi-units. The bottom trace represents a pressure curve. Mean changes in the duration (b) and frequency (c) of responses are presented. Error bars represent S.E. n=9. B: Nociceptive discharges were recorded in the PFC of the side ipsilateral to 6-OHDA injection. There was no difference in mean nociceptive responses between the control (n= 8) and 6-OHDA groups (n=10). Error bars represent S.E.
Sogabe et al. BMC Neuroscience 2013 14:65 doi:10.1186/1471-2202-14-65