Figure 5.

Etanercept decreased FPI-induced increases in the number of co-localization of microglia and TNF-α specific marker cells in ischemic hypothalamic regions. Representative panel staining at 72 h after FPI, respectively, (A) a sham operation rat, (B) for a FPI+saline rat and (C) a FPI+etanercept rat (D) The TBI+saline group (▤) showed a significant increase of the numbers of co-localization of microglia and TNF-α specific marker cells cells in the ischemic hypothalamus 72 h after TBI compared with the sham controls (■) (*P < 0.01). The FPI+etanercept group (▩ ) showed a significant decrease of the numbers of co-localization of microglia and TNF-α specific marker cells compared with the FPI+saline group (▤) (+P < 0.01). Each column and bar is the mean ± SD of eight rats per group.

Chio et al. BMC Neuroscience 2013 14:33   doi:10.1186/1471-2202-14-33
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