Table 1

Physiological parameters of rats subjected to ischemia
Treatment Before occlusion After recirculation After bolus injection 5 h after ischemia 72 h after ischemia
mean arterial pressure (mmHg) vehicle 123.4 ± 22.1 125.1 ± 21.8 123.7 ± 14.3
EPO 111.0 ± 9.7 116.75 ± 15.3 103.3 ± 11.8
temperature (°C) vehicle 37.82 ± 0.3 38.05 ± 0.5
EPO 37.49 ± 0.9 37.62 ± 0.5
pCO2 (kPa) vehicle 4.82 ± 0.96 5.55 ± 1.01 4.73 ± 0.6 5.77 ± 0.41 5.92 ± 0.48
EPO 5.26 ± 1.45 5.75 ± 1.1 5.28 ± 1.89 5.79 ± 0.63 6.35 ± 0.66
pO2 (kPa) vehicle 17.37 ± 2.57 17.05 ± 3.99 16.67 ± 3.08 16.84 ± 5.33 15.15 ± 2.05
EPO 17.86 ± 2.64 17.69 ± 2.58 17.61 ± 3.05 17.4 ± 4.53 15.23 ± 2.77
pH vehicle 7.43 ± 0.07 7.34 ± 0.15 7.47 ± 0.06 7.42 ± 0.04 7.44 ± 0.02
EPO 7.43 ± 0.07 7.43 ± 0.06 7.46 ± 0.1 7.43 ± 0.03 7.43 ± 0.05
HCO3- vehicle 24.32 ± 0.87 26.02 ± 2.72 26.27 ± 1.76 27.1 ± 1.69 29.0 ± 0.7
EPO 25.88 ± 1.39 27.16 ± 1.38 27.68 ± 0.92 27.60 ± 1.05 29.36 ± 1.53
Hb (g/l) vehicle 159.8 ± 6.61 148.0 ± 11.79 152.0 ± 9.12 145.57 ± 9.45 125.67 ± 4.73*
EPO 149.57 ± 8.1 133.86 ± 9.99 147.0 ± 5.24 141.67 ± 13.49 132.46 ± 27.52
HCT (%) vehicle 48.9 ± 2 45.4 ± 3.5 46.6 ± 2.8 44.6 ± 2.8 38.7 ± 1.5*
EPO 45.0 ± 3.2 41.8 ± 2.6 44.2 ± 3.1 42.7 ± 4.5 42.3 ± 5.4
glucose (mmol/l) vehicle 5.88 ± 2.7
EPO 7.05 ± 1.6
treatment before occlusion 7 days after ischemia
body weight (g) vehicle 332.0 ± 8.3 335.1 ± 17.5
EPO 345.0 ± 18.3 332.9 ± 18.9

Data are presented as means ± standard deviation at the time of recirculation. Statistical differences are indicated. No indications are given if no difference was observed between the treatment groups. *p = 0.0002 vs vehicle treatment before occlusion.

Undén et al.

Undén et al. BMC Neuroscience 2013 14:27   doi:10.1186/1471-2202-14-27

Open Data