IGFBP-2 Expression Following Hypoxic-Ischemic Injury. Brain sections of mice from either the Sham group or the MCAO group were used to visualize IGFBP-2 in neurons, astrocytes and microglia. All images were taken of cells in the cortex that formed the penumbra. (A, B) Neurons are co-labeled with anti-NeuN and anti-IGFBP-2. (C) Astrocytes are co-labeled with anti-GFAP and anti-IGFBP-2. (D) Microglia are co-labeled with anti-Iba-1 and anti-IGFBP-2. Bars represent 20 μm.
Fletcher et al. BMC Neuroscience 2013 14:158 doi:10.1186/1471-2202-14-158