Additional file 3: Figure S3.
Synergistic phosphorylation of Erk and JNK upon combinatorial NGF (0-50 ng/ml) and PACAP (0-100 ng/ml) treatments. Fold changes of (a) pErk, and (b) pJNK under (i) uni-ligand treatments, (ii) bi-ligand treatments at 10ng/ml of NGF, and (iii) bi-ligand treatments at 50 ng/ml NGF. Significant differences between combinatorial experimental treatment of NGF-PACAP and summation of their individual effects were calculated using the paired Student’s t-test. A value of p<0.05 was considered significant (**p<0.01).
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Seow et al. BMC Neuroscience 2013 14:153 doi:10.1186/1471-2202-14-153