Schema of the dopaminergic neve cell model. The dopaminergic nerve cell model contains 111 metabolites (red and pink circles) and 139 reactions (rectangles). The different sub-models are labeled and indicated in different colors. Metabolites and reactions that are surrounded by multiple colors are assigned to multiple sub-models. The most strongly interconnected part of the model is in the middle and consists of αSYN, ROS, damaged proteins, and mitochondria.
Büchel et al. BMC Neuroscience 2013 14:136 doi:10.1186/1471-2202-14-136