Gal80 control of Gal4 dependent UAS-dNSF2E/Q morphological phenotypes. Typical immunofluorescent images of (A) wild-type and (B) elavGal4 > UAS-dNSF2E/Q Drosophila larval neuromuscular junctions (NMJ). Muscle 6, 7, and 13 are labeled. The dNSF2E/Q neuromuscular junctions are significantly overgrown compared to wild-type. (C) Total NMJ length was measured and quantified for the indicated genotypes from larvae raised continuously at either 25° or 30°C. At 25°C the presence of Gal80 suppresses the elavGal4 > UAS-dNSF2E/Q driven overgrowth, whereas at 30°C the NMJs remain overgrown (black bars).
Laviolette and Stewart BMC Neuroscience 2013 14:124 doi:10.1186/1471-2202-14-124