Effect of age on caudate volume. Illustrated here are the correlations between the age of the subjects and the caudate nucleus volume in the sighted (SI – top panel) and blind (AB: all blind subjects combined – bottom panel) subjects respectively. While there is a significant negative correlation between both measures in the sighted, indicating an age-related decline in caudate volume, the correlation in the blind (both CB and LB combined) is much weaker and did not reach statistical significance.
Voss et al. BMC Neuroscience 2013 14:113 doi:10.1186/1471-2202-14-113