Additional file 1: Figure S1.
Regional construct expression and processing. Example of coronal section stained with 6E10 of homozygous ETNA animals at the age of 3 months. Most severe immunoreactivity is found in the striatum (A). Also amygdala (B) showed strong Aβ expression and pE3-Aβ formation is observed at later time points. In hippocampus Aβ positive cells were observed in the pyramidal cell layer (C), but no pE3-Aβ could be observed up to the age of 9 months. In cortex (D) and brainstem (E) single positive cells were found.
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Becker et al. BMC Neuroscience 2013 14:108 doi:10.1186/1471-2202-14-108