Table 3

Schizophrenia gene set network properties
Up-regulated (25) Down-regulated (69)
CTL SZ CTL SZ
Node degree
Mean 63.9 83.5 127.4 106.2
Non-interacting nodes 2 2 7 3
Edges (within gene set) 12 23 129 144
Shortest Path
Mean 3.28 3.14 3.31 3.48
Random gene set comparison
Z-score −0.58 −0.91 3.15 4.46
p-value 0.23 0.15 0 0
Cluster Coefficient
Mean 0.35 0.38 0.32* 0.27*
Random gene set comparison
Z-score 1.11 2.47 1.51 −0.607
p-value 0.14 0.005 0.06 0.28

*Difference is significant between CTL and SZ at p = 0.05.

Mistry et al.

Mistry et al. BMC Neuroscience 2013 14:105   doi:10.1186/1471-2202-14-105

Open Data