Dopamine and dopamine metabolites are reduced in the striatum of mGlu2/3-/- mice. (A) Dopamine content is reduced in the striatum of mGlu2/3-/- mice (black) compared to wildtype mice (white), n = 14 WT, 16 KO. Dopamine metabolites DOPAC (B) and HVA (C) are also reduced. Monoamine concentration is normalised to the tissue weight in mg. Graphs show mean ± SEM; all one-way ANOVA, *p=0.023; **p<0.005.
Lane et al. BMC Neuroscience 2013 14:102 doi:10.1186/1471-2202-14-102